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Serie: Resveratrol

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Literatur/Studien-Verzeichnis

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Kundu, J. K., Surh, Y.-J., Molecular basis of chemoprevention by resveratrol: NF-kappaB and AP-1 as potential targets. Mutat. Res. 555 (2004) 65-80. 

Jang, M. S., et al., Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275 (1997) 218-220. 

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Dorrie, J. C., et al., Resveratrol induces extensive apoptosis by depolarizing mitchondrial membranes and activating caspase-9 in acute lymphoblastic leukaemia cells. Cancer Res. 61 (2001) 4731-4739. 

Mahyar-Roemer, M., Kohler, H., Roemer, K., Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells. BMC Cancer 2 (2002) 27-36. 

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Anderson, R. M., et al., Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423 (2003) 181-185. 

Langley, E., et al., Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 21 (2002) 2383-2396. 

Howitz, K. T., et al., Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425 (2003) 191-196. 

Wood, J. G., et al., Sirtuin activators mimic calorie restriction and delay ageing in metazoans. Nature 430 (2004) 686-689. 

Araki, T., Sasaki, Y., Milbrandt, J., Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305 (2004) 1010-1013. 

Baur, J. A., et al., Resveratrol improves health and survival of mice on a high-calorie diet. Nature Vol. 444 (2006) 337-342. 

Walle, T., et al., High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab. Dispos. 32 (2004) 1377-1382. 

Mertens-Talcott, S. U., Percival, S. S., Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells. Cancer Lett. 218 (2005) 141-152. 

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Crowell, J. A., et al., Resveratrol-associated renal toxicity. Toxicol. Sciences 82 (2004) 614-619.

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